Liposomal Vitamin B9

Liposomal Vitamin B9 - Advanced Folate Supplementation Solution

Welcome to BioSpark (Xi'an) Biotechnology Co., Ltd. If you're searching for a highly bioavailable folate supplement, you've come to the right place. Our Liposomal Vitamin B9 represents a breakthrough in nutritional science. Not at all like conventional folic corrosive, this progressed equation employments nano-encapsulation innovation to provide (6S)-5-methyltetrahydrofolate (5-MTHF) - the dynamic shape your body can utilize quickly. With over 95% bioavailability, the item bypasses hereditary restrictions and conveys prevalent comes about for your wellbeing needs. Whether you're arranging pregnancy, supporting cardiovascular wellbeing, or overseeing particular supplement prerequisites, our item offers you a experimentally approved solution.​​​​​​​

Product Description

Our premium folate supplement highlights pharmaceutical-grade 5-MTHF typified inside a phospholipid bilayer. This modern conveyance framework secures the dynamic fixing from debasement whereas upgrading absorption.

Key Specifications:

• Active Ingredient: 5-Methyltetrahydrofolate (5-MTHF)
• Concentration: 5% (verified by HPLC)
• Particle Size: 85±10nm with PDI ≤0.12
• Encapsulation Efficiency: ≥95%
• Appearance: Light yellow to orange-yellow fine powder
• Solubility: Water-dispersible
• Purity: ≥98% with optical purity ≥99.5%

The phospholipid framework incorporates hydrogenated soy phosphatidylcholine (HSPC), DSPE-PEG2000 for amplified circulation, and cholesterol for layer soundness. Our definition contains trehalose as a defensive specialist and keeps up strict quality guidelines with overwhelming metal limits well underneath administrative thresholds.

Application Areas

Your health goals determine how our product can serve you:

Maternal and Prenatal Health

Support your pregnancy journey from preconception through postpartum recovery. Our formula reduces neural tube defect risks by up to 72-100% and supports healthy fetal development.

Cardiovascular Wellness

Manage homocysteine levels effectively. Clinical studies show 25-30% reduction in plasma homocysteine, supporting vascular health and reducing stroke risk by 24%.

Cognitive Function

Maintain brain wellbeing as you age. Investigate illustrates 18% advancement in memory scores and 34% slower cognitive decrease rates.​​​​​​​

Clinical Nutrition

Address particular therapeutic needs counting megaloblastic frailty, MTHFR quality transformations, and dietary bolster for patients with assimilation disorders.

Functional Foods & Beverages

Fortify your product lines with stable, bioavailable folate for cereals, dairy products, beverages, and specialized nutrition products.

Benefits

When you choose our product, you receive multiple advantages:

Superior Bioavailability

Your body absorbs our 5-MTHF directly without requiring enzymatic conversion. Bioavailability exceeds 95%, with peak blood levels 4.8 times higher than traditional folic acid.

Genetic Compatibility

Even if you carry MTHFR gene mutations (677TT or 1298CC), our formula maintains over 90% effectiveness. Traditional folic acid often fails for these individuals.

Enhanced Stability

Our liposomal technology protects the active ingredient. After UV exposure, retention remains ≥98%. Thermal stability testing shows less than 2% degradation after 30 days at 60°C.

Rapid Action

Experience faster results with a shortened absorption time (Tmax) of just 1.2 hours and an extended half-life of 8-10 hours.

Safety Profile

Your partnership with BioSpark brings you distinct competitive advantages:

Technological Excellence

We've mastered advanced liposomal encapsulation with 32 critical process control points. Our stepwise extrusion system produces uniform particles with precise size distribution. Real-time monitoring through Process Analytical Technology ensures consistent quality.

Market Expertise

With a decade serving the European, American, and Asian markets, we understand your regulatory requirements and consumer preferences. Our formulations comply with FDA, EU Organic, NSF-GMP, and Chinese Blue Hat certifications.

Supply Reliability

Our 5A-level factory maintains over 1,000 tons of conventional raw materials and 100,000 boxes of finished products. Standard products ship within 10 days. Custom orders launch within 15 days and deliver within 30 days.

Comprehensive ODM/OEM Services

We offer total customization beginning from fair 100 boxes or kilograms. Select from different measurement shapes - gummies, capsules, powders - with bundling alternatives from eco-friendly to premium blessing boxes. Territorial adjustment guarantees your items meet nearby inclinations and regulations.​​​​​​​

Global Coordinations Network

Through associations with DHL, FedEx, and specialized cold-chain suppliers, we convey door-to-door arrangements. Coordinate shipping lines to EU and US arrive inside 15 days. Our traditions clearance rate surpasses 99%.

Certificates

Our quality credentials demonstrate our commitment to excellence:

• ISO9001 Quality Management System
• FDA Registration
• NSF-GMP Certification
• EU Organic Certification
• Kosher Certification
• Halal Certification
• Chinese Blue Hat Approval
• FSSC22000 Food Safety System

All certificates are available for verification at any time.

Quality Control

We implement rigorous quality assurance at every stage:

Raw Material Standards

USP-grade (6S)-5-MTHF calcium salt with ≥98% purity undergoes antioxidant treatment under nitrogen protection. Filtration through 0.22μm PVDF membranes removes all microorganisms and particles.

Process Monitoring

Our seven-step production process includes precise temperature control (±1°C), pH monitoring (7.2-7.6), and online particle size tracking. Ultracentrifugation at 220,000×g achieves >99% free drug removal.

Testing Methods

High-performance liquid chromatography (HPLC), UPLC-MS/MS for trace detection (LOD=0.1ng/mL), dynamic light scattering for particle characterization, and Karl Fischer coulometric method for moisture analysis.

Sterility Assurance

Dual sterilization through 0.22μm membrane filtration and aseptic filling in Class A clean areas (ISO 4). Bacterial endotoxin levels stay below 0.25 EU/mL.

Certificate of Analysis (COA)

Each batch includes comprehensive testing data:

• 5-MTHF content (≥95%)
• Particle size distribution (D50=87nm, PDI≤0.12)
• Zeta potential (-38±4mV)
• Encapsulation efficiency (≥95%)
• Moisture content (≤1.5%)
• Heavy metals (As, Pb, Cd, Hg)
• Microbial testing (sterility, endotoxin, mycoplasma)

  ProductName:	Liposomal Vitamin B9
  BatchNumber:	GH03	Quantity:	100kg
  Source:	Folic Acid (Vitamin B9)	Package:	25kg/Drum
  ManufactureDate:	N.nth.2025	ExpiryDate:	N.nth.2027
  ITEMS	STANDARD	RESULTS	METHOD
  Assay	5%	Conforms	HPLC
  Physical Control
  Appearance	Light yellow to orange-yellow fine powder	Conforms	Visual
  Odor	Natural smell and Characteristic	Conform	Organoleptic
  Mesh Size	100% pass 40 mesh	Conform	Mesh screen or equivalent
  grain size	100-300nm	Conform	Electron micrographs
  Loss on Drying	≤8%	2.4%	Eur.Ph.7.0 [2.8.17]
  Ash	≤5%	1.9%	Eur.Ph. <2.4.16>
  Bulk Density	0.55-0.6	Conform	Weighing Method
  Chemical Control
  Total Heavy Metals	≤10 ppm	Conforms	ICP-MS or equivalent or GB
  As	≤1ppm	0. 10ppm	ICP-MS or equivalent or GB
  Pb	≤2ppm	0. 10ppm	ICP-MS or equivalent or GB
  Cd	≤1ppm	0. 07ppm	ICP-MS or equivalent or GB
  Hg	≤0. 1ppm	0.005ppm	ICP-MS or equivalent or GB
  Microorganism Control
  Total Plate Count	≤1000 cfu/g	Conforms	AOAC or equivalent or GB
  Yeast and Mold	≤100 cfu/g	Conforms	AOAC or equivalent or GB
  Coliforms	Negative	Negative	AOAC or equivalent or GB
  E.Coli	Negative	Negative	AOAC or equivalent or GB
  Staphylococcus	Negative	Negative	AOAC or equivalent or GB
  Salmonella	Negative	Negative	AOAC or equivalent or GB
  Conclusion
  Standard	Conform with specification.
  Storage	Store in cool and dry places. Keep away from strong light and heat.
  Packing	Pack in 25kgs paper-drums, inner by double plastic bag
  Shelf life	24 months under the above condition,and in it’s original package

• Stability data

Packaging and Transportation

Standard Packaging:

• Primary: 25kg/drum in neutral borosilicate glass with fluoropolymer-coated seals
• Secondary: Aluminum-plastic composite bags with desiccants
• Nitrogen protection system (residual oxygen ≤0.5%)

Shipping Options:

Express (DHL/FedEx/UPS) for samples and urgent orders

Air freight for medium volumes (5-10 working days)

Ocean freight for bulk orders (20-45 days, most economical)

Multimodal solutions optimizing cost and speed

Trade Terms:

We support EXW, FCA, FOB, CIF, CFR, CPT, DDP, and DAP to match your logistics preferences.

Storage Conditions:

Long-term: -20°C (36-month validity)

Working storage: 2-8°C protected from light

After-Sales Service

Your success matters to us. We provide Liposomal Vitamin B9:

Technical Support

Component testing reports, efficacy verification schemes, and production process optimization guidance help you develop superior products.

Regulatory Assistance

We assist with regulatory declarations in your target markets, label design compliance, and market access consultation.

Quality Guarantee

Two-year warranty on finished products with full traceability from raw materials to delivery.

Responsive Communication

Order responses within 48 hours and complete solutions within 72 hours ensure your projects stay on schedule.

R&D Results

Our innovation partnership with leading universities drives continuous formula development. Key achievements include:

• Joint laboratory projects advancing liposomal delivery systems
• Multi-center human feeding trials validating efficacy
• Cell experiment verification of mechanisms
• Proprietary extraction and purification technologies
• Next-generation formulations for specialized applications

This collaborative approach ensures you receive cutting-edge products that maintain competitive advantages in your market.

FAQ

Q: How does liposomal conveyance vary from normal folic acid?

A: Our liposomal framework secures 5-MTHF amid absorption and significantly increments retention. Normal folic corrosive requires different enzymatic transformations that numerous individuals cannot perform efficiently.

Q: Who benefits most from this product?

A: People with MTHFR quality transformations, ladies arranging pregnancy or pregnant, individuals overseeing cardiovascular wellbeing, elderly populaces concerned almost cognitive work, and anybody looking for predominant folate bioavailability.

Q: What is your least arrange quantity?

A: We oblige orders beginning from 1kg for testing purposes. For commercial generation, ODM/OEM administrations start at 100 boxes or kilograms.

Q: Can you customize formulations?

A: Completely. We offer total customization counting concentration alteration, dose frame choice (capsules, tablets, powders, fluids), combination with complementary supplements, and bundling design.

Q: How do you guarantee item soundness amid shipping?

A: Temperature-controlled transportation, nitrogen security, light-blocking bundling, and associations with specialized cold-chain coordinations suppliers keep up item judgment all through delivery.

Q: What documentation do you give for traditions clearance?

A: Total trade documentation counting commercial receipt, pressing list, certificate of examination, wellbeing certificate, certificate of root, and significant quality certifications for your goal nation.

Contact Us

Ready to elevate your product line with superior folate supplementation? Our team stands ready to support your success.

Email: sales@biosparkcn.com

Whether you need technical specifications, custom formulation consultation, sample requests, or partnership discussions, we respond within 48 hours with comprehensive solutions tailored to your requirements.

Experience the BioSpark difference - where scientific innovation meets reliable partnership. Contact us today to discover how our Liposomal Vitamin B9 can transform your product offerings and deliver exceptional value to your customers.

BioSpark (Xi'an) Biotechnology Co., Ltd - Your trusted partner in advanced nutritional solutions. Serving global markets with a decade of expertise in plant extraction and health food innovation.